Ampicillin Trihydrate Compacted or Powder CAS 7177-48-2
Ampicillin Trihydrate Powder
Ampicillin Trihydrate Compacted
White crystalline powder.
Ampicillin Trihydrate is practically insoluble in alcohol, in ether and in fatty oils, slightly soluble in water. Ampicillin dissolves in dilute solutions of acids and of alkali hydroxides.
96.0% ~ 100.5%
Enzyme Method and Chemical Method
Smaller particle size
Larger particle size
Ampicillin Trihydrate (Ampicillin, Ampicilline) is a traditional anti-bacterial substance. It can be use to make Antibacterial Preparations. For example, Ampicillin Capsules, Ampicillin Oral Suspension, Capsules, Co-fluampicil Oral Suspensions.
Ampicillin Trihydrate is roughly equivalent to amoxicillin in terms of activity.
Ampicillin Trihydrate will penetrate Gram-positive and some Gram-negative bacteria.
It differs from penicillin G, or benzylpenicillin, only by the presence of an amino group. That amino group helps the drug penetrate the outer membrane of Gram-negative bacteria.
Ampicillinis in thepenicillingroup ofbeta-lactam antibiotics. It belongs to theaminopenicillinfamily.
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Ampicillin Trihydrate is bactericidal at low concentrations and is clinically effective not only against the gram-positive organisms usually susceptible to penicillin G but also against a variety of gram-negative organisms. It is stable in the presence of gastric acid and is well absorbed from the gastrointestinal tract. It diffuses readily into most body tissues and fluids; however, penetration into the cerebrospinal fluid and brain occurs only with meningeal inflammation. Ampicillin Trihydrate is excreted largely unchanged in the urine; its excretion can be delayed by concurrent administration of probenecid which inhibits the renal tubular secretion of Ampicillin Trihydrate. In blood serum, Ampicillin Trihydrate is the least bound of all the penicillins; an average of about 20 percent of the drug is bound to the plasma proteins as compared to 60 to 90 percent of the other penicillins.
Indication and usage:
Ampicillin Trihydrate raw material can be used to produce Ampicillin Trihydrate capsules, Ampicillin Trihydrate for Oral Suspension.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Ampicillin Trihydrate capsules, Ampicillin Trihydrate for Oral Suspension and other antibacterial drugs, Ampicillin Trihydrate capsules and Ampicillin Trihydrate for Oral Suspension should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. When culture and susceptibility information are available, they should be considered in selecting of modifying anitimicrobial therapy, in the absence of such data, local epidemiology and susceptibility patterns contribute to the empiric selection of therapy.
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